Side effects of JAK inhibitors identified so far include stomach upset, an increase in chest and skin infections and transaminaitis (an alteration in liver function identified by blood testing). Mild skin and upper respiratory tract infections have been reported in 25% of patients. Very few patients with alopecia areata elect to stop the medication as a result of side effects. Nevertheless patients receiving these medications require close medical supervision.

About 2 years ago my hair started thinning. I thought it was because I was in college and stressed. At that point I started going what is known as “CG” in the curly hair world. I no longer color, flat iron, use sulfates and I rarely blow-dry and use silicones. I use shampoos and conditioners with beneficial ingredients, not fillers. After 1.5 years on this Curly Girl routine, I experienced some relief and noticed my hair getting thicker. That lasted a couple months and now I’m back to losing a ton of hair. One day I counted 160 hairs…that was on a decent day. I’m sure I’ve lost 2x that amount before. My hair is noticeably thinner, drier, and it knots. It NEVER use to knot. I think my hair has become finer too, but I’m not positive. It just feels more fragile.
Typical first symptoms of alopecia areata are small bald patches. The underlying skin is unscarred and looks superficially normal. Although these patches can take many shapes, they are usually round or oval.[6] Alopecia areata most often affects the scalp and beard, but may occur on any part of the body with hair.[7] Different areas of the skin may exhibit hair loss and regrowth at the same time. The disease may also go into remission for a time, or may be permanent. It is common in children. 

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I am 31; as a child I had beautiful brown smooth hair with a hint of a wave. As soon as I hit puberty at 13 (1st period on my 13th b-day), my hair turned wavier. Same year, I remember looking down on my legs horrified at the hair I had developed. Only 1 thought came to me: “NOT NORMAL!” Body hair on women is a tricky subject, though, with media heavily influencing what’s considered ‘normal’. My mom, similarly hairy, just told me it’s genetic and normal.
Many other agents have been used to treat alopecia areata, including minoxidil, psoralen plus ultraviolet A (PUVA), and anthralin (Anthra-Derm), but success rates vary. Anthralin, an anti-psoriatic, in combination with topical corticosteroids and/or minoxidil, is a good choice for use in children and those with extensive disease because it is relatively easy to use and clinical irritation may not be required for efficacy.6 Hairpieces and transplants may be the only options available for persons with severe disease that remains unresponsive to available medical treatments. Patients with recalcitrant, recurrent, or severe disease should be referred to a subspecialist.
I am so sorry you’ve been so down. I’ve had some other troubles lately that have been bringing me down so the hair loss almost seems so much less important right now. I may lose my home to foreclosure in the next month so I’m focused right now on getting that resolved and trying to stay out of foreclosure. Then I can go back to focusing on my hair again! ha!
Hi I need help I am not sure what doctor I need to see, one day I started to have lots of back pain and my lower left side real bad I went to bed and when i shower lots of my hari started to fall off, I mean I loose my hair but not as much and I just wanted to cry when I saw lots and lots coming out. My hair is so thin now and you can see the bald spots im ony 35 and Im not sure if its my hormones or not. Can someone help me and let me know which doctor is best to see for hair loss
Finally people who understands what I am going through …I am in a desperate search for doctors in the Miami/Boca Raton, Florida area. Can anyone help? I dont know yet what has been causing my hair loss…I had been loosing some hair throighout the years, and sometimes it gets lees severe but lately has just gotten worse and there is no stopping it seems. I had mt Tyroid checked by PCP a coulpe months ago and my iron level also looked normal …getting desperate. Would appreciate some help.
Thank you all for sharing, For the pass years I have been having hair loss on and off. I have tried several natural treatment, example : hot oil , moist heat, acupuncture. Have seen several doctors and specialists which cost me thousands of dollars. I have insurance, but they will not accept, because they will not get pay, it is experimental my insurance paid for my lab tests. at this time my diagnosis is hypothyroidism. I am using organic foods, juicing; sunflowers seeds , pumpkin seed to make smoothie and oils from doTerra to massage my scalp. trying vitamins etc. etc. I cannot pinpoint what makes the improvement because I have used
The scalp is where each hair follicle receives its blood supply, allowing it to grow strong. If you show your scalp a little TLC and make sure it's nourished, hydrated and healthy, then your hair will be stronger and more resistant to breakage, promoting healthy growth. Foods packed with vitamin E, like almonds, walnuts and raspberries or strawberries, are great for promoting scalp circulation, as are vitamin C-rich foods like kiwis and broccoli. Walnuts also are a great source of zinc—zinc deficiency can cause shedding—so they’re extra powerful.
have something to say that sounds alarming: I came to the Texas to live 10 weeks ago from the UK. Within only 2 weeks of being here my hair started falling out dramatically, I would lose around 500 to 700 hairs every time I washed my hair, this would also include hair lost through blow drying as I got to the point I would sweep it up off the floor too. Before I left the UK my hair was beautifully silky and shiny and looked so healthy. Over the following 8 weeks the hair loss worsened to the extent I started getting so dramatically thin all over the top of my head that I got myself into a panic every time I would do out as I didn’t want anyone to see me this way as I am quite an attracted woman 38 years of age. My periods are normal and my health appears good, just now I am suffering from depression because of this. The point I am making here is, I never had this in my life before, sure I have had bouts of hair fall from stress but never has it ever got to the point I can no-longer go out ever. I see so many things about this on the TV here in Dallas always advertising women’s hair loss? I also see too much of this on the net also from the US that now I am really getting worried about ever coming here and if this continues I’m going to leave the US and never come back. The people here are so lovely so please don’t get me wrong just that my health and my hair come first. I have visited the US many times and been to many States over the recent years from California to FL to Chicago and each time I come over I start to lose my hair. Bit this time is the worst ever! When I Skype my family back home they are shocked of course and we are all wondering if it is the food chain, the water, the air, pollution, I mean it’s got to be something right? I also spent years over in Brasil and also Lima Peru but never had anything like this, in fact my hair got even better over there than from when I was in the UK last. I’ve got a strong suspicion the doctor’s over here know more than they are letting on and have done for a long time but just making money out of peoples misery. I saw a doctor here who did some blood works and charged me $800 and he didn’t even do a hormone profile or (Ferritin) as checking iron is a total waste of time, Ferritin is the end response of iron absorption. Checking iron in the blood is what is floating around and not what has been absorbed. He wanted to then send me onto an Endo who wanted to charge me another $400. for a consult plus she said anything from $600. for additional blood works. I Lima Peru I can get 10 x more blood works done for no more than $120. Be cheaper for me to get a return flight and have all the tests done over there. Sorry to say this but, the US is a total rip-off when it comes to this sort of thing. Everyone back home thinks the whole thing stinks and sounds very suspect. If my hair gets any worse I’m defo going leave and most likely head on to Lima for a while and then go set my roots in Brasil. I really wanted to be here in the US as I have so many lovely friends over here and could really see a future for me here. I am gutted. Anyways I’m going to do some research to see if I can find a good Endo myself as well as a dermatologist. Maybe it is all to I do with all the nuclear testing they did years ago? they say radiation remains for a 100 years and what with weather conditions, wind, rain, crops, livestock, water supply? Now we have phytoestrogens and now we have this other thing to worry about frankenfoods. Us women have a more complex hormone system than males and this has got to wreak havoc on our endocrine system our glands and of course our hormones. I believe whatever is causing this must be doing something to us internally that is the cause. So lotions and potions working from the outside is not the answer or a permanent solution. I think something is disrupting us from the inside and screwing with our hormones be it thyroid, sex hormones or whatever. So stop sugar drinks, artificial foods and water from plastic bottles, microwave foods and start to clean up your health from the inside and perhaps try find organic meat, vegetable, fruit, fish suppliers. Maybe little more costly, but far cheaper than giving the money to a bunch of quacks? I guess thank goodness for European rules and regulations on food compared to here. Like to hear peoples thoughts.
Androgenetic alopecia (AGA), or male-pattern baldness, is hair thinning in an “M”-shaped pattern; hair loss occurs on the temples and crown of the head with sparing of the sides and back5 (Figure 2). This pattern reflects the distribution of androgen-sensitive follicles in most people.6 Starting at puberty, androgens shorten the anagen phase and promote follicular miniaturization, leading to vellus-like hair formation and gradual hair thinning.6

Hair: It’s a natural part of being a human. But when the temperature climbs, and skin is exposed, it’s one of those things that a good many of us want to control. This week, we’re tackling hairlessness, not just the process of hair removal (electric shavers and ingrown-hair treatments and aesthetician-approved tweezers) but also what to buy when you’re losing your hair, and even how to take care of a Sphynx cat. Here, we’re talking to dermatologists and hair-loss doctors about hair-loss treatments that actually work.
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