Side effects of JAK inhibitors identified so far include stomach upset, an increase in chest and skin infections and transaminaitis (an alteration in liver function identified by blood testing). Mild skin and upper respiratory tract infections have been reported in 25% of patients. Very few patients with alopecia areata elect to stop the medication as a result of side effects. Nevertheless patients receiving these medications require close medical supervision. 

Hi,this is really tough for me and I don’t know what to say. I have always lost a lot of hair but I had a ton of hair. However,my mom commented that she noticed that it has thinned out more than usual and it has. And today, I just took picture of the top of my head and see a spot. Like you Lisa, I am completely freaked out, I am two weeks away from my 34th birthday. Sorry, Lisa I don’t know of any doctors except for my dermatologist that I am calling tomorrow and I found an endocrinologist through United Healthcare that I will call. I’m so upset that the crying just won’t stop. What worries me is that I’ve been on aladactone for about a year for acne (but was only at 50 mg) BUT she did up the dosage about 5 months ago (but only consistently take at the 200 mg for 3 months). But my fear is that the aladactone didn’t help prevent it for me. But the thinning out has been noticeable since about May/June of this year so maybe there is hope. Now, I have to put in there I went through a very stressful period from March until now. And had a rapid weight loss of 35 pounds (went from 168 to 133) and I’ve been doing a lot of running. But my concern is my sister has female pattern balding and so does my mom so I am very worried. My sister said the doctor said to up her protein and get super b-12 complex which I started two weeks ago, my sister said she has seen some regrowth. Today, I went and got biotin, magnesium and iron. And bought Nioxin shampoo as i heard it help give the appearance of more hair. I am calling the doctors tomorrow in hopes that it really was just my rapid weight loss, I have to admit I was under a lot of stress and barely eating, I’m eating better now though but again it runs in my family and I am completely freaked out. Lisa if I have any success I will let you know who my doctors were. Know that I too, live in Phoenix and am going through the same thing. It is hard, now I am afraid my boyfriend will leave me. Keep faith.
As mentioned above, an autoimmune response is commonly associated with hair loss related to alopecia areata. Patients who have this condition see their body’s immune system attack their hair follicles. The patient’s hair follicles become very small and hair growth begins to stop.  A major symptom of alopecia areata is patchy hair loss, according to the American Academy of Dermatology, which says patients often first notice the problem when they see clumps of hair on their pillow or in the shower.
One day in my mid 20s I got feed up with my at that point frizzy hair. I took a close look at individual hairs. I almost had a heart attack. Again this thought:”NOT NORMAL!!” I had tons of KINKY, ROUGH, even ZEBRA-STRIPED hair!! Much resembling pubic hair. The striped hairs were few, but they were literally striped in the darkest shade of brown I have & white!
In either sex, hair loss from androgenetic alopecia occurs because of a genetically determined shortening of anagen, a hair's growing phase, and a lengthening of the time between the shedding of a hair and the start of a new anagen phase. (See "Life cycle of a hair.") That means it takes longer for hair to start growing back after it is shed in the course of the normal growth cycle. The hair follicle itself also changes, shrinking and producing a shorter, thinner hair shaft — a process called "follicular miniaturization." As a result, thicker, pigmented, longer-lived "terminal" hairs are replaced by shorter, thinner, non-pigmented hairs called "vellus."

The only nonchemical option offered up by the dermatologists I spoke with — short of a surgical hair transplant or platelet-rich plasma therapy, which is like Kim Kardashian’s vampire facial but for your scalp — was the laser comb. First cleared by the FDA in 2009, the HairMax LaserComb is a handheld laser device that is designed to promote hair growth. As the manufacturer explains in a letter to the FDA, “The device provides distributed laser light to the scalp while the comb teeth simultaneously part the user’s hair to ensure the laser light reaches the user’s scalp,” which, in turn, stimulates the hair follicles.


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Alopecia areata, also known as spot baldness, is a condition in which hair is lost from some or all areas of the body.[1] Often it results in a few bald spots on the scalp, each about the size of a coin.[2] Psychological stress may result.[2] People are generally otherwise healthy.[2] In a few, all the hair on the scalp or all body hair is lost and loss can be permanent.[1][2]

You ARE the same inside, but you are also different… you’ve been through a lot and it is so difficult to to stay strong through this experience. I won’t even go into the hair stuff, because it sounds to me that this is not what your post is about. You need to get some really solid support and find something other than your hair to focus on. You need an awesome hair system…and support system. From there, I hope and pray for you, that you will be able to find happiness and balance in your life again. You are a glorious human…don’t doubt that for a moment!
There is no cure for the condition.[2] Efforts may be used to try to speed hair regrowth such as cortisone injections.[1][2] Sunscreen, head coverings to protect from cold and sun, and glasses if the eyelashes are missing is recommended.[2] In some cases the hair regrows and the condition does not reoccur.[2] In others hair loss and regrowth occurs over years.[2] Among those in whom all body hair is lost less than 10% recover.[5]
One more disease that causes hair loss is male pattern baldness. About two out of three men, experience hair loss by their age of 60 and most of the time, the hair loss is because of male pattern baldness. Such type of hair loss, caused by a combo of genes and male sex hormones, usually follow a classic pattern where the hair recedes at the temples, thus leaving an M-shaped hairline.

Because of its psychologic nature, the mainstays of treatment are counseling, behavior modification techniques, and hypnosis. Selective serotonin reuptake inhibitors and other medications for depression or obsessive-compulsive disorder may be used in some cases, although no medications are FDA-approved for treatment of trichotillomania.17 If a more moth-eaten appearance of hair loss is present and no evidence of hair-pulling behavior can be elicited, syphilis should be suspected.


About 2 years ago I lost approximately 50% of my hair and the quality went from thick, strong, straight, healthy hair to thin, weak, frizzy, kinky dry hair that not only sheds but breaks and flakes off pieces at my ends. My skin has become very dry and my nails have become weak also. I went to an endocronologist that put me on 125mg spironolactone which had been increased slowly over a period of a year. He also decided he wanted to give me a layered approach by adding on 2 other medications over a year, one was Glumetza ER 500mg twice a day and Actos 15mg once a day. He said my DHEA was a little high and that these drugs used for off label treatment would help grow my hair back. My hair stopped falling out and a little grew back but the quality of my hair was still very sickly almost like someone on a chemo drug. I was concerned about my liver and stopped taking the drugs, unfortunately my hair started shedding again.

What a helpful website, thank you ladies for sharing. I am 55 and am loosing hair by handfuls when I shampoo. I have been using Minoxodil extra strength for about 5 years and it was helping but not anymore. I also have been taking Nioxin hair vitamins and they helped for the first 3 years but not now. I am going to check out Dr Redmond like several of you recommended and head to Sallys for hair extensions also. Does anyone know of a good Dermotologist or Endo Dr. in Humble or Kingwood Tx area? Karen
I am a 33yr old woman who has been losing hair for the past few years. I have spent so much money on bad doctors, vitamins that I just did not know what to do? I just had an appointment with Dr. Redmond (NYC) – he prescribed kariva (birth control – low estrogen) and 200 mg of spiro. He told me it will take 2-4months for the shedding to stop and to see some regrowth. I am hopeful. Before him, I went to see Dr. Berkowitz, he put me on a natural steroid pregnolone that REALLy made my hair fall out and created a bald spot. Has any one tried Kariva/mircette?
Telogen effluvium is the second most common type of hair loss. It is predominantly seen in women between the ages of 40-70, but may occur at any age. Its symptoms include excessive thinning, shedding, and balding and it may happen abruptly. Common causes of sudden hair loss include changes in hormone levels such as with child birth, menopause, poor nutrition, medical conditions such as iron deficiency anemia and hypothyroidism, medications, severe illness or infection, major surgery, and even extreme levels of stress.
I am 45 years-old and started noticing a thinning of my hair about 2 years ago. I did see a dermatologist specialized in hair loss and was only prescribed a testosterone lab test which came back normal. My scalp is vey itchy but I do not have dandruff or any signs of dry skin. It sometimes hurts so bad I wake up at night. I was prescribed a steroid shampoo and a steroid lotion which have helped calm down the itchiness and pain if used regularly. I was diagnosed with Female baldness (mostly on the top which is really thin now) and dermatitis. not further explanations. I was also prescribed Rogaine 5% and a mixture of Rogaine and RA to use every 3 days. once a day. should I start using them twice a day? its only been 3 months and I have not noticed a change. I accepted a job to work from home because I was getting too self conscious to go to work at the office. I am very concerned by my appearance usually but this hair loss is a constant worry.
Each day the scalp hair grows approximately 0.35 mm (6 inches per year), while the scalp sheds approximately 100 hairs per day, and more with shampooing.1 Because each follicle passes independently through the three stages of growth, the normal process of hair loss usually is unnoticeable. At any one time, approximately 85 to 90 percent of scalp follicles are in the anagen phase of hair growth. Follicles remain in this phase for an average of three years (range, two to six years).1 The transitional, or catagen, phase of follicular regression follows, usually affecting 2 to 3 percent of hair follicles. Finally, the telogen phase occurs, during which 10 to 15 percent of hair follicles undergo a rest period for about three months. At the conclusion of this phase, the inactive or dead hair is ejected from the skin, leaving a solid, hard, white nodule at its proximal shaft.2 The cycle is then repeated.
Many other agents have been used to treat alopecia areata, including minoxidil, psoralen plus ultraviolet A (PUVA), and anthralin (Anthra-Derm), but success rates vary. Anthralin, an anti-psoriatic, in combination with topical corticosteroids and/or minoxidil, is a good choice for use in children and those with extensive disease because it is relatively easy to use and clinical irritation may not be required for efficacy.6 Hairpieces and transplants may be the only options available for persons with severe disease that remains unresponsive to available medical treatments. Patients with recalcitrant, recurrent, or severe disease should be referred to a subspecialist.
SOURCES: George Cotsarelis, MD, director, Hair and Scalp Clinic, University of Pennsylvania School of Medicine, Philadelphia. Andrew Kaufman, MD, assistant professor, department of dermatology, University of California, Los Angeles; medical director, Center for Dermatology Care, Thousand Oaks, Calif. Tom Barrows, PhD, director of product development, Aderans Research Institute Inc., Atlanta. Cotsarelis, G. and Millar, S.E. Trends in Molecular Medicine, July 2001; vol 7: pp 293-301. American Society for Dermatologic Surgery web site. American Academy of Facial and Reconstructive Plastic Surgery web site. American Hair Loss Council web site. Springer, K. American Family Physician, July 1, 2003; vol 68: pp 93-102. Hair Loss Help web site, "Interview with Dr. Ken Washenik from Bosley." Fuchs, E. Developmental Cell, July 2001: vol 1: pp 13-25.
I was searching the internet and came across this wonderful site. I really appreciate you posting this article. I have always had a small bald patch on one side of my head. My mom told me it had always been there so I didn’t worry about it. Recently it has been getting larger and the hair around it is getting lighter. On the other side my hair is thinning and the color and texture is changing. It also seems to be falling out. I have excessive hair loss on a regular basis. I am only 24 years old and I can’t stand that my hair is falling out. I went to the dermatologist and he gave my injections but they didn’t work. He said I have alopecia areata and that the other side was a normal receding hairline. (He barely even looked at it) He then told me after the injections weren’t working to try Rogaine. I think it might be helpful to see an endrocrinologist as I have also been having problems with anemia. Again, thank you so much for the information you have provided.
"Dr. Yaker was extremely personable as well as knowledgeable on hair and hair health. With his treatment plan that was tailored to my needs and requests, I have noticeable thicker and fuller hair within three months! His enthusiasm towards his work was very comforting. He truly puts the patient at the center of care he delivers and it doesn't go unnoticed! I would highly recommend him as your physician if you are struggling with the appearance of your hair!"

Greetings ladies, I am so happy I found this website. I have a 19 year old daughter who has been experiencing hair loss for the past 5 years. Throughout high school, she wore hair weave to camouflage what was going on. She is now a sophomore in college and wants to wear her natural hair. It is frustrating her because we don’t know why its happening. Does anybody know of a good endocrinologist in Chicago? Do you think treatments varies depending on ethnicity? She is African American.
About 2 years ago my hair started thinning. I thought it was because I was in college and stressed. At that point I started going what is known as “CG” in the curly hair world. I no longer color, flat iron, use sulfates and I rarely blow-dry and use silicones. I use shampoos and conditioners with beneficial ingredients, not fillers. After 1.5 years on this Curly Girl routine, I experienced some relief and noticed my hair getting thicker. That lasted a couple months and now I’m back to losing a ton of hair. One day I counted 160 hairs…that was on a decent day. I’m sure I’ve lost 2x that amount before. My hair is noticeably thinner, drier, and it knots. It NEVER use to knot. I think my hair has become finer too, but I’m not positive. It just feels more fragile.
*All medications have both common (generic) and brand names. The brand name is what a specific manufacturer calls the product (e.g., Tylenol®). The common name is the medical name for the medication (e.g., acetaminophen). A medication may have many brand names, but only one common name. This article lists medications by their common names. For information on a given medication, check our Drug Information database. For more information on brand names, speak with your doctor or pharmacist.
If a pregnant woman comes in contact with crushed or broken Finasteride tablets, wash the contact area right away with soap and water. If a woman who is pregnant comes into contact with the active ingredient in Finasteride, a healthcare provider should be consulted. If a woman who is pregnant with a male baby swallows or comes in contact with the medicine in Finasteride, the male baby may be born with sex organs that are not normal.
Harklinikken (“hair clinic” in Danish) inspires great loyalty. Four out of five users come as referrals from satisfied customers, said Lars Skjoth, the company’s founder and chief scientist. The results are certainly compelling. After four months of daily application — that is, working the tea-colored tonic into the hair section by section, then letting it sit on the scalp for six hours — most users regain at least 30 percent of lost density, and some as much as 60 percent, according to company figures.
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