Side effects of JAK inhibitors identified so far include stomach upset, an increase in chest and skin infections and transaminaitis (an alteration in liver function identified by blood testing). Mild skin and upper respiratory tract infections have been reported in 25% of patients. Very few patients with alopecia areata elect to stop the medication as a result of side effects. Nevertheless patients receiving these medications require close medical supervision.
The truth is, the amount of propylene glycol in hair loss treatments is not likely to cause any real harm and the FDA has given the chemical approval for many uses. But even though it is safe, we wanted to ensure that our top picks would be as comfortable to use as possible. So when Dr. Khadavi told us that “a third of my patients get irritated from minoxidil products because of propylene glycol,” we decided to cut any treatments with it. In any case, it’s the minoxidil that helps curb hair loss and not the propylene glycol.
Dr. Williams is also the primary investigator in a National Institute of Health (NIH) approved IRB study in regenerative medical treatment procedures with stem cell/stromal therapy for hair loss in androgenetic alopecia. A new study treating scaring and autoimmune (Alopecia Areata) alopecia is expected in 2017. Dr. Williams believes the foundations of health and hair restoration are founded on prevention and wellness. His primary practice is hair restoration surgery in Orange County, and he is involved in teaching medical students and residents from various medical training programs in northern and southern California. He is on the clinical teaching faculty of Western University of Health Science in Pomona, California; and Touro University College of Osteopathic Medicine in San Francisco, California, and Chapman University new Health Science teaching facilities.
The general medical consensus around laser treatments — caps and combs alike — is that low-level laser light therapy stimulates the cells within the hair follicle. These devices may also increase cell metabolism to promote thicker and more durable hair shafts, something that neither minoxidil or finasteride can do. To use the HairMax Ultima, all you have to do is glide the device over your scalp slowly. Treatments should take about eight minutes, and you should do it three days per week for the best results.
Laser devices: Brushes, combs, and other hand-held devices that emit laser light might stimulate hair growth. These devices might make hair look more youthful in some people. Because the FDA classifies these products as medical devices, the products do not undergo the rigorous testing that medicines undergo. The long-term effectiveness and safety for these devices are not known.
I”m sitting here reading all your letters hoping that you’ve helped someone and hoping that you can help me, too. I’m 48 and all my life I’ve been told how beautiful my hair was. I now live in S Florida and within the last couple of years I stopped styling my hair because of the heat and the humidity. I usually wear it in a ponytail (never tight – I’m sure that’s not the problem). About a year ago I noticed athat a lot of hair was on the back of my car seat.I mean A LOT.When I went home to NY I tried to style my hair like I used to and it didn’t work. It just layed there.The more I looked I noticed how thin it was. I came back to Fl and went to a dermatologist who barely looked at me and told me to try rogaine.
Alopecia areata occurs when your immune system attacks your hair follicles, causing varying degrees of hair loss. Alopecia areata usually starts with one or more small, round, smooth bald patches on your head, and can eventually cause complete hair loss on your scalp or even on your entire body. Full body hair loss is known as alopecia universalis. 

Leprosy (Hansen's disease) is a disfiguring disease caused by infection with Mycobacterium leprae bacteria. The disease is spread from person to person through nasal secretions or droplets. Symptoms and signs of leprosy include numbness, loss of temperature sensation, painless ulcers, eye damage, loss of digits, and facial disfigurement. Leprosy is treated with antibiotics and the dosage and length of time of administration depends upon which form of leprosy the patient has.

I too have suffered from hair loss, more noticebly over the past 2 year, although it first started 10 years ago. I am 39 female and always had a full head of hair. Now, my hair has gone dry, dull and and has lost it volume. I have been to my Dr and have had test done, however everything has come back ok. i.e. my hair los was not found to be down to any internal deficiencies hormones, nutrient levels, diseases etc , so now my Dr is referring me to a dermatoligst to see if the problem is due to the skin on my scalp. However it maybe advisable if you havent already, to visit a licesend Trichologist, this is someone who specifically deals with the scientific study of the health of hair and scalp, and would have a more thorough knowledge about your hair than any GP and by conducting a hair analysis, can identify your hair loss problem. I intially visited, and it was he who suggested I go along to my GP and ask for specific types of tests. However, he also informed me for some cases there are conditions that can be cured, but with other, it could simply be that hair loss pattern is heriditary which can occur in both male and female ( this does not necessarily need to come from your parents or grandparent, it could come from family gene from generations back, that so happened to show up in you generations later!). In this case, the frank truth is little can be done. However there are different topical treatments, and people do not have to go to the extreme of hair surgery or even having to wear undignified wigs. Below is a link to a product called Toppik which I have used. Basically it small fibre which are made from the same fibres as natrual hair, which use sprink onto your hair to cover bald and thinning areas. It adds body, volume, and makes your hair ‘magically’ appear full regardless of the lenghth of your hair. Its not expensive, and also come with conditoner and shampoo to give your hair that added volume, even to the most thinnest of hair. I hope this will provide some solution and even comfort to those experiencing hair loss. The link is below – Good luck
Women also may experience AGA, often with thinning in the central and frontal scalp area but usually without frontal–temporal recession (Figure 3). A history and physical examination aimed at detecting conditions of hyperandrogenism, such as hirsutism, ovarian abnormalities, menstrual irregularities, acne, and infertility are indicated. Laboratory tests are of little value in women with AGA who do not have characteristics of hyperandrogenism.5
CURRENT REGIMEN: 6 weeks ago I purchased Hair Essentials… and am seeing some fine hair growth. Weight loss & exercise can also heighten follicular dormancy. (Have lost 90 lbs. in the last year.) Important to maintain 50-60mg/daily protein levels, as well as routine multi-vitamin, higher levels of B-Complex, D and Calcium levels while dieting… heavily impacts hair, nails & skin. Am researching possible relationship between gastrointestinal health and hair loss.
Hi,this is really tough for me and I don’t know what to say. I have always lost a lot of hair but I had a ton of hair. However,my mom commented that she noticed that it has thinned out more than usual and it has. And today, I just took picture of the top of my head and see a spot. Like you Lisa, I am completely freaked out, I am two weeks away from my 34th birthday. Sorry, Lisa I don’t know of any doctors except for my dermatologist that I am calling tomorrow and I found an endocrinologist through United Healthcare that I will call. I’m so upset that the crying just won’t stop. What worries me is that I’ve been on aladactone for about a year for acne (but was only at 50 mg) BUT she did up the dosage about 5 months ago (but only consistently take at the 200 mg for 3 months). But my fear is that the aladactone didn’t help prevent it for me. But the thinning out has been noticeable since about May/June of this year so maybe there is hope. Now, I have to put in there I went through a very stressful period from March until now. And had a rapid weight loss of 35 pounds (went from 168 to 133) and I’ve been doing a lot of running. But my concern is my sister has female pattern balding and so does my mom so I am very worried. My sister said the doctor said to up her protein and get super b-12 complex which I started two weeks ago, my sister said she has seen some regrowth. Today, I went and got biotin, magnesium and iron. And bought Nioxin shampoo as i heard it help give the appearance of more hair. I am calling the doctors tomorrow in hopes that it really was just my rapid weight loss, I have to admit I was under a lot of stress and barely eating, I’m eating better now though but again it runs in my family and I am completely freaked out. Lisa if I have any success I will let you know who my doctors were. Know that I too, live in Phoenix and am going through the same thing. It is hard, now I am afraid my boyfriend will leave me. Keep faith.
@Amanda P. I regrew my hair and you can too. -I've been bleaching my hair on and off since forever. My hair wouldn't grow any longer it would just snap off. I've dreamed about having thick, long hair. And when I say dreamed, I mean it quite literally. So i decided to do something about it. My friend suggested Biotin when we were talking about my hair loss.
There are many potential causes of hair loss in women , including medical conditions, medications, and physical or emotional stress. If you notice unusual hair loss of any kind, it's important to see your primary care provider or a dermatologist, to determine the cause and appropriate treatment. You may also want to ask your clinician for a referral to a therapist or support group to address emotional difficulties. Hair loss in women can be frustrating, but recent years have seen an increase in resources for coping with the problem.
I just came across this website and would welcome any recommendations on hair loss specialists in the suburbs of Philadelphia, PA. I have an appointment with my family doctor in a couple weeks, and I’m sure she’s going to run blood work. I’m a 55 yo female and have been experiencing large amounts of hair loss in the past few months. I am generally in good health with the exception of some “structural” issues (scoliosis, etc.). Thank you!
There are numerous nonsurgical treatments that when combined, can offer significant hair improvements. Dr. Yaker’s TCHR Volumizing Glycolic Acid Shampoo and Conditioner help restore vitality to the hair by deep cleaning the scalp and reestablishing lost moisture content and physiological pH to the scalp and hair. Dr. Yaker has also formulated his own oral supplement, which is a blend of Aminoplex hair repair vitamins. This is made up of amino acids (building blocks of protein) that produce keratin, which makes up close to 97% of our hair. In addition, Dr. Yaker’s specially compounded FDA approved topical medication, Minoxidil (brand name: Rogaine®), is clinically proven to help slow down, stop and even reverse hair loss in women. Other nonsurgical therapies offered are Low Level Laser Therapy (LLLT) using the advanced LaserCap®, and Platelet Rich Plasma (PRP) with placenta-derived extracellular matrix therapy to help restore thinning hair. Lastly, Dr. Yaker offers scalp and facial micropigmentation where permanent ink is applied to the skin, creating micro dots that replicate the natural appearance of hair. This is used for the scalp and eyebrows.
My hair was healthy. No split ends and thick and tame – I could not break it. The healthy condition of my hair may be the reason that I didn’t loose all of it. My hair loss was due to a “HAIR DESTROYER” causing chemical damage, burning my scalp and my hair ( I think she used a product banned in Australia). I had bald spots on my crown the size of 50 cent pieces and the rest of my hair was singed. I lost my hair gloss, I was left with hair that was as thin a rice paper and breaking everywhere. I had severe itching on my scalp for two years. Not pleasant. I cursed her every day and still do. I bought myself a pair of hairdressing scissors and cut as much hair off as I could; and chipped into it everywhere. I do this every two weeks. Hence I will never go to a hair dresser again and have not colored my hair since December 2012 – I asked for Brown on Brown 10 vol – how could an idiot of a hair destroyer (dresser) get it so wrong.
I am on Arava and my hair has become extremely coarse, frizzy, and tight tight curls in the back. The sides of my hair are pure frizz and the top is straight, with frizz. It used to be smooth and so easy to manage. Now it takes so long and it looks awful. Anyone find the same thing and anything that helps? I have tried so very many hair products, so has my beautician. She says it is like I have 3 completely different textures on my head.
There can be several factors behind hair loss such as environmental effects, aging, too much stress, excessive smoking, nutritional deficiencies, hormonal imbalance, genetic factors, scalp infections, use of wrong or chemically enriched hair products, certain medicines and medical conditions like thyroid disorder, autoimmune diseases, polycystic ovary syndrome (PCOS), iron-deficiency anemia, and chronic illnesses.
Hi,this is really tough for me and I don’t know what to say. I have always lost a lot of hair but I had a ton of hair. However,my mom commented that she noticed that it has thinned out more than usual and it has. And today, I just took picture of the top of my head and see a spot. Like you Lisa, I am completely freaked out, I am two weeks away from my 34th birthday. Sorry, Lisa I don’t know of any doctors except for my dermatologist that I am calling tomorrow and I found an endocrinologist through United Healthcare that I will call. I’m so upset that the crying just won’t stop. What worries me is that I’ve been on aladactone for about a year for acne (but was only at 50 mg) BUT she did up the dosage about 5 months ago (but only consistently take at the 200 mg for 3 months). But my fear is that the aladactone didn’t help prevent it for me. But the thinning out has been noticeable since about May/June of this year so maybe there is hope. Now, I have to put in there I went through a very stressful period from March until now. And had a rapid weight loss of 35 pounds (went from 168 to 133) and I’ve been doing a lot of running. But my concern is my sister has female pattern balding and so does my mom so I am very worried. My sister said the doctor said to up her protein and get super b-12 complex which I started two weeks ago, my sister said she has seen some regrowth. Today, I went and got biotin, magnesium and iron. And bought Nioxin shampoo as i heard it help give the appearance of more hair. I am calling the doctors tomorrow in hopes that it really was just my rapid weight loss, I have to admit I was under a lot of stress and barely eating, I’m eating better now though but again it runs in my family and I am completely freaked out. Lisa if I have any success I will let you know who my doctors were. Know that I too, live in Phoenix and am going through the same thing. It is hard, now I am afraid my boyfriend will leave me. Keep faith.
Loss of hair from the eyelashes could be caused by an underlying medical condition—or from pulling at your lashes (e.g. from curling lashes, from glues used for false lashes, and from tugging to remove mascara or false lashes). Whatever the reason, we regularly treat thinning lashes by prescribing Latisse®—the first, and only, FDA-approved treatment for thinning lashes. Our patients have reported excellent results (fuller, longer, darker lashes) with this cream. (Note: if you wear contact lenses, you can use Latisse®; you just need to remove the contact lenses before application and re-insert them at least 15 minutes after applying.) Just contact our office to speak with one of DR.DENNIS GROSS about whether Latisse® is right for you. Also important to note: Latisse® is currently in clinical trials as a treatment for hair loss on the scalp. It could be available for this use within the next couple of years.
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Hi I need help I am not sure what doctor I need to see, one day I started to have lots of back pain and my lower left side real bad I went to bed and when i shower lots of my hari started to fall off, I mean I loose my hair but not as much and I just wanted to cry when I saw lots and lots coming out. My hair is so thin now and you can see the bald spots im ony 35 and Im not sure if its my hormones or not. Can someone help me and let me know which doctor is best to see for hair loss
Thank you Diana. If you find out any more information, I would appreciate it. I have a dermatologist across the street from the Skin and Cancer Institute. I’m still not sure who to start with, the dermatologist or an endocronologist. I left a message for my PCP today to see if she is comfortable working with female hair loss or if not if she could refer me to someone who specializes in it. I will let you know what I hear back. In the meantime, thanks for your support. Take care.
I was searching the internet and came across this wonderful site. I really appreciate you posting this article. I have always had a small bald patch on one side of my head. My mom told me it had always been there so I didn’t worry about it. Recently it has been getting larger and the hair around it is getting lighter. On the other side my hair is thinning and the color and texture is changing. It also seems to be falling out. I have excessive hair loss on a regular basis. I am only 24 years old and I can’t stand that my hair is falling out. I went to the dermatologist and he gave my injections but they didn’t work. He said I have alopecia areata and that the other side was a normal receding hairline. (He barely even looked at it) He then told me after the injections weren’t working to try Rogaine. I think it might be helpful to see an endrocrinologist as I have also been having problems with anemia. Again, thank you so much for the information you have provided.

Many factors can contribute to hair disorders. Alopecia, or hair loss, may be caused by medical conditions such as lupus, thyroid disorder, protein or iron deficiencies, or hormonal imbalances.  Hirsutism -- abnormal hair growth in women (such as a beard or chest hair) -- may be caused by ovarian, adrenal, thyroid or pituitary conditions. Identifying the cause, and treating the condition are our goal. 
I”m sitting here reading all your letters hoping that you’ve helped someone and hoping that you can help me, too. I’m 48 and all my life I’ve been told how beautiful my hair was. I now live in S Florida and within the last couple of years I stopped styling my hair because of the heat and the humidity. I usually wear it in a ponytail (never tight – I’m sure that’s not the problem). About a year ago I noticed athat a lot of hair was on the back of my car seat.I mean A LOT.When I went home to NY I tried to style my hair like I used to and it didn’t work. It just layed there.The more I looked I noticed how thin it was. I came back to Fl and went to a dermatologist who barely looked at me and told me to try rogaine.
Hello. Chris, I am so happy that you made an appt to see Dr. Redmond. How did it go? I really hope it helped. i have been on treatment now for almost 3 months. Dr. Redmond told me to be patient, that things could take a year to improve, but I do feel mostly that things have stabilized. In my work (i am a physician) I have seen alot of sad cases in the last few weeks. Young patients with major illnesses, some possibly incurable and fatal. It has made me really sad. It has also made me realize that regardless of what is happening to my hair, I have to try and be happy. I have to be thankful that I am healthy and have wonderful family and friends. Not that it is a consolation, but for us, our illness is on the surface and not life threatening…unless we make it by the psychological part. Thank you for everyone who has contributed to this website so that I can deal with the psychological part better. I am doing research into wigs now and will let all of you know when I have more info. Supposedly there is a soap opera star who was bald at 14 and has been wearing wigs for a long time. She has made a line of wig’s I think called Amy’s presence. It seems that she has led a happy life despite her hairloss. Once I found out more, I will let you know. I know its not a cure, but at least it is a remedy. One day at a time, I know we can all get through this. Be well.
Please help. My hair has always been my pride and joy. I figured since it is pretty damn healthy, it could deal with some bleach damage. And I figured the master stylist who did all the color-corrections would know how much would be too much. I was wrong, and now I want to burst into tears every time I look at my hair or touch it. I just don't know what to do. my hair has also NEVER been shorter than this and it breaks and falls out. What should i do to regrow hair?
Thank you Diana. If you find out any more information, I would appreciate it. I have a dermatologist across the street from the Skin and Cancer Institute. I’m still not sure who to start with, the dermatologist or an endocronologist. I left a message for my PCP today to see if she is comfortable working with female hair loss or if not if she could refer me to someone who specializes in it. I will let you know what I hear back. In the meantime, thanks for your support. Take care.
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I’m 42 and I noticed my front top and sides thinning about a year ago – a lot coming out when brushing after washing. I went to the doctor who happened to be African-American (I’m caucasion) and she actually asked me if I wore “corn rows” a lot! Needless to say, she was worthless and just prescribed me something for dandruff, which I do not have! I went to an endocrinologist to see if my thyroid or menopause was the problem – tests turned out honky dorie! Now I can see through the top of my head when the sun shines on it (scar-y) and I’m having to cover over the temple areas with sweeps of hair from the other side (interesting, the right side is much thinner). I will say that I’ve gone through hell and back with a mentally ill young adult but if it was stress, wouldn’t it have come out quicker than just in the last year (I’ve been dealing with his illness for 7 years now)?? I’ve heard that sometimes it takes 2 or 3 blood tests and doctors to finally see that one has thyroid problems. Is this the experience of others, and would I be throwing my money away by seeing my general practitioner?
I got really sick at the age 40, 2 years after my second child was born,I started losing weight,I went from 54kg down to 47kg,my skin was splitting on the backs of my legs,both my hands,I had blisters up my arms ,on the tops of my feet,migraines that would have me vomiting none stop for ten hours,then only to sleep for 2 days to recover,no doctors were interested,I saw 8 and they all wanted me on anxiety medication because I was going through a break up that was there answer to the way I was feeling.No one wanted to listen to me.Almost feeling like
What a helpful website, thank you ladies for sharing. I am 55 and am loosing hair by handfuls when I shampoo. I have been using Minoxodil extra strength for about 5 years and it was helping but not anymore. I also have been taking Nioxin hair vitamins and they helped for the first 3 years but not now. I am going to check out Dr Redmond like several of you recommended and head to Sallys for hair extensions also. Does anyone know of a good Dermotologist or Endo Dr. in Humble or Kingwood Tx area? Karen
I have been losing my hair over this past year but within the last 6 months it has changed texture and still falling out! Now my hair is very coarse and kinky! For 42 years I had long straight-as-a-board hair and now I look like a poodle! Every time I comb or brush my hair handfuls of hair comes out! My hairdresser, gyno, GP and 3 dermatologists have told me it was normal to lose this amount of hair! Many contribute it aging but I find that hard to believe. Finally, my most recent derm said I was low in iron and said that might be a factor. Now, I’m going in to see if I might be anemic. My gyno ran the same tests and said all seemed normal! It’s the most frustrating and stressful event, especially when everyone tells you things are “normal”! Has anyone experienced their hair texture changing over a short period of time? Thanks-

If you find yourself snacking at night before bed, it may be because you're bored or anxious — not truly hungry — and eating makes you feel better. Try eating a healthy dinner a bit later in the evening. If your stomach is truly growling before bed, try a protein-based snack like a hard-boiled egg or a slice of cheese. A few spoonfuls of yogurt or some fruit is another good option. 


Hello. Chris, I am so happy that you made an appt to see Dr. Redmond. How did it go? I really hope it helped. i have been on treatment now for almost 3 months. Dr. Redmond told me to be patient, that things could take a year to improve, but I do feel mostly that things have stabilized. In my work (i am a physician) I have seen alot of sad cases in the last few weeks. Young patients with major illnesses, some possibly incurable and fatal. It has made me really sad. It has also made me realize that regardless of what is happening to my hair, I have to try and be happy. I have to be thankful that I am healthy and have wonderful family and friends. Not that it is a consolation, but for us, our illness is on the surface and not life threatening…unless we make it by the psychological part. Thank you for everyone who has contributed to this website so that I can deal with the psychological part better. I am doing research into wigs now and will let all of you know when I have more info. Supposedly there is a soap opera star who was bald at 14 and has been wearing wigs for a long time. She has made a line of wig’s I think called Amy’s presence. It seems that she has led a happy life despite her hairloss. Once I found out more, I will let you know. I know its not a cure, but at least it is a remedy. One day at a time, I know we can all get through this. Be well.


I just came across this website, I thought by chance but I think not! I have been having scalp pain, like my skull wanted to crack open. Then the tendersness of my hair folicals when the wind would blow. I started to loose lots of hair so went to my family doctor. All the test were done for Thyroid problems…all turned out what they call “normal”. Have you seen the wide range which is considered normal? How can this be when everyone is so different? I am loosing hair as I sit and write this message. The hair just gently falling onto my shoulder. I need to color my hair as it is time from the length of my silver roots but the last time I had my hair touched up, I thought I was going to die from the pain when the stylist tried to just shampoo the color off. Oh my God! Painful, painful. I used to be a stylist so you can imagine my shock when I was told it wasn’t my Tyroid!

Hair transplants will likely lead to better results in the long run (you are introducing new hairs to the balding areas), but you’ll still need to use minoxidil or finasteride after surgery to maintain the results. Like all hair loss treatments, hair transplants are best when combined with other methods, and you’ll want to speak with your doctor to see what combination is best for you.
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The topical sensitizers, diphencyprone or squaric acid dibutylester, have been used in those suffering from recalcitrant alopecia areata or those with more than 50% hair loss. The goal of treatment is to create an allergic contact dermatitis of the scalp. This alteration in the immune response occasionally is accompanied by hair regrowth. The efficacy of the topical sensitizers has been demonstrated in both young children and adults, but it probably works less than half the time. Recent success using oral janus kinase inhibitors, including tofacitinib, ruxolitinib, and baricitinib, have been shown to be efficacious in severe, extensive alopecia areata in adults, but long-term therapy has potential side effects. The durability of response to these medications is variable, and most patients experience recurrence of hair loss after discontinuation. Perhaps topical therapy with these types of drugs may be available in the near future.
Figure 2 is used with permission from Utah Valley Family Practice Residency Program.Figures 3 and 10 are used with permission from the Utah Valley Family Practice Residency Program. Figure 5 is used with permission from Mark Luba, M.D., Good Samaritan Family Practice Residency. Figure 6 is used with permission from Richard Usatine, M.D., UCLA. Figures 9 and 11 are reprinted with permission from the American Academy of Dermatology.
When alopecia areata is associated with celiac disease, treatment with a gluten-free diet allows for complete and permanent regrowth of scalp and other body hair in many people, but in others there are remissions and recurrences.[15] This improvement is probably due to the normalization of the immune response as a result of gluten withdrawal from the diet.[15]
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