In 2010, a genome-wide association study was completed that identified 129 single nucleotide polymorphisms that were associated with alopecia areata. The genes that were identified include those involved in controlling the activation and proliferation of regulatory T cells, cytotoxic T lymphocyte-associated antigen 4, interleukin-2, interleukin-2 receptor A, and Eos (also known as Ikaros family zinc finger 4), as well as the human leukocyte antigen. The study also identified two genes, PRDX5 and STX17, that are expressed in the hair follicle.[18]

What is a Dermatologist? A certification by the Board of Dermatology; practitioners treat pediatric and adult patients with disorders of the skin, mouth, hair and nails as well as a number of sexually transmitted diseases. They also have expertise in the care of normal skin, the prevention of skin diseases and cancers, and in the management of cosmetic disorders of the skin such as hair loss and scars.

"Firstly, even the very good ones won’t get to the root of the issue - pardon the pun - and prevent or treat male or female pattern baldness which is caused by genetics, nor deal with hormonal issues at the heart of female hair loss. But they can help make the hair you do have stronger and healthier. And they can be useful in putting a hair loss regime in place, along with medication like Minoxidil or Finasteride and/ or a hair transplant.
Diffuse female hair thinning and hair loss during premenopausal age is usually not heredity. It is usually caused by hormonal imbalances seeing in PCOS or thyroid disorder, nutritional deficiency (low iron), and stress. Women with PCOS produce high levels of androgens such as testosterones and DHEAS. The ratio of LH and FSH is also more than 2. Make sure you get your sex hormones check if you notice your hair thinning.
Corticosteroids: This medicine suppresses the immune system. It can be given as shots, with the dermatologist injecting the medicine into the places with hair loss. Sometimes a patient gets a topical (applied to the skin) form of this medicine. It may be a cream, lotion, or ointment. The patient applies the medicine to the bare spots. Less often, patients take corticosteroid pills.
When alopecia areata is associated with celiac disease, treatment with a gluten-free diet allows for complete and permanent regrowth of scalp and other body hair in many people, but in others there are remissions and recurrences.[15] This improvement is probably due to the normalization of the immune response as a result of gluten withdrawal from the diet.[15]
SOURCES: George Cotsarelis, MD, director, Hair and Scalp Clinic, University of Pennsylvania School of Medicine, Philadelphia. Andrew Kaufman, MD, assistant professor, department of dermatology, University of California, Los Angeles; medical director, Center for Dermatology Care, Thousand Oaks, Calif. Tom Barrows, PhD, director of product development, Aderans Research Institute Inc., Atlanta. Cotsarelis, G. and Millar, S.E. Trends in Molecular Medicine, July 2001; vol 7: pp 293-301. American Society for Dermatologic Surgery web site. American Academy of Facial and Reconstructive Plastic Surgery web site. American Hair Loss Council web site. Springer, K. American Family Physician, July 1, 2003; vol 68: pp 93-102. Hair Loss Help web site, "Interview with Dr. Ken Washenik from Bosley." Fuchs, E. Developmental Cell, July 2001: vol 1: pp 13-25.
Let me give a background of my health issues. I am 54 years old and I was diagnosed with Hashimoto’s (hypothyroid) disease AND going through menopause about 6 years ago. I have a great ob/gyn that will treat both using compounded bio-identical hormones. I have bloodwork at least twice a year, more if I’m not feeling 100%. My testosterone levels were usually on the low side, but still WNL.
Around 30 million U.S. women will experience hereditary hair loss, or female pattern baldness (androgenetic alopecia), while others will struggle with situational hair loss, brought on by medical conditions, medications, poor health and nutrition, environmental factors such as smoking and sun damage, or even from adverse reactions to hair care products or treatments.
Hair loss (alopecia) affects men and women of all ages and often significantly affects social and psychologic well-being. Although alopecia has several causes, a careful history, close attention to the appearance of the hair loss, and a few simple studies can quickly narrow the potential diagnoses. Androgenetic alopecia, one of the most common forms of hair loss, usually has a specific pattern of temporal-frontal loss in men and central thinning in women. The U.S. Food and Drug Administration has approved topical minoxidil to treat men and women, with the addition of finasteride for men. Telogen effluvium is characterized by the loss of “handfuls” of hair, often following emotional or physical stressors. Alopecia areata, trichotillomania, traction alopecia, and tinea capitis have unique features on examination that aid in diagnosis. Treatment for these disorders and telogen effluvium focuses on resolution of the underlying cause.

Alopecia areata is a disease that attacks your hair follicles (the part of your skin that makes hair). In most cases, hair falls out in small, round patches about the size of a quarter. This causes only a few bare patches. Some people may lose more hair. In only a few people, the disease causes total loss of hair on the head or loss of all body hair.
Ann, I’m so sorry to hear about your home. That breaks my heart for you. I wish you the best in recovery of your home and blessings on your finances. But I do have to say I think that only losing 20 sounds like a dream! I absolutely know that my TE was triggered by PPD in hair dye. I only wish that I would have figured it out sooner. I was forewarned with itching for a year, no dandruff flaking or anything just itching and that was my body trying to heal itself against the allergy and the all hell broke lose on my head! Please keep me posted propecia; I wouldn’t even look for any improvement for 6 months though. But please be here when you do see it! Have a blessed day!
I’ve been glued to these stories for hours now b/c they’re so similar to my own. My hair has always been thin but straight and manageable and for months now it’s texture has changed to frizzy, broken and very fragile. Needless to say the bald spots cannot be covered even with toppik so I’ve resorted to a wig for work and some social events. Dr’s have been totally unhelpful telling me that I’ve now gotten thyroid imbalance corrected. A naturopath has recommended a gluted free diet and PRP. Any results in either arena??? Thanks for this opportunity to share and compare.

My hair started thining out this past year. I notice my hair falling out when i got pregnant with my son. I got diabetes with my pregnancy. my scalp itches and it hurts. It feels like i had my hair tied up so tight and let it go. it hurts to move my hair. i saw a dermatologist and said it was due to the stress of child birth. it has been over a year and is still falling out. has anyone heard of this and what i can do. My Pcp check my hormone levels and said everything is fine. I need help.
*Photograph used with permission of the Journal of the American Academy of Dermatology. This photograph was published in the Journal of the American Academy of Dermatology, Vol. # 60, Gathers RC, Jankowski M, Eide M, et al. “Hair grooming practices and central centrifugal cicatricial alopecia,” 660-8. Copyright Elsevier (2009). Journal of the American Academy of Dermatology.   

Hi everyone, I am a 19 years old girl that is loosing my hair. I started to lose my hair since I was 14. once 18 I decided to go for a hair transplant surgery. I wanted to feel as any another girl and be confident. I went to bosley may 2007 and did the surgery. They told me it will take 6 to 8 months for my new hair to grow few inches. I went there after 6 and after 8 months but unfortunatly we havent seen any growing hair yet. The doctor told me that it depends from one person to another and it might take me from 12 to 15 months. I went to see him yesterday and by then it was almost 15 months… he walked in looked at my hair didnt say any word for a while and then told me: “I am going to give you your money back” I cried right away for a while I couldnt take it. I haddreams and hope. I imagined my life differently after the surgery. Anyways all that to tell you guys if you wanna go for a hair restoration AVOID BOSLEY. I live in boston nd went to the bosley place in the newbury street. I believed them because of all their advertising. Now i dont even know what to do. School is almost starting and i dont feel like going. I wanna look nice and feel relaxed. I feel the pain every morning before going to school. I cry every night when I get home. I need to find a solution. i thought about extensions but cant go for them cuz i am scared to lose more hair. My God help us!
From doing this I have noticed less hair loss, some re-growth and some thickness, more coverage on the crown area, you cannot see the baldspots any more but just a long faint scalp line. But I will not go to a hairdresser or put colour in my hair. I believe this is why my hair is improving. I didn’t spend money on doctors or dermatologists and certainly will never give money to a hairdresser again. I use products with no parabens and sulfates. I hope my post helps; please try not to give up.
My hair was healthy. No split ends and thick and tame – I could not break it. The healthy condition of my hair may be the reason that I didn’t loose all of it. My hair loss was due to a “HAIR DESTROYER” causing chemical damage, burning my scalp and my hair ( I think she used a product banned in Australia). I had bald spots on my crown the size of 50 cent pieces and the rest of my hair was singed. I lost my hair gloss, I was left with hair that was as thin a rice paper and breaking everywhere. I had severe itching on my scalp for two years. Not pleasant. I cursed her every day and still do. I bought myself a pair of hairdressing scissors and cut as much hair off as I could; and chipped into it everywhere. I do this every two weeks. Hence I will never go to a hair dresser again and have not colored my hair since December 2012 – I asked for Brown on Brown 10 vol – how could an idiot of a hair destroyer (dresser) get it so wrong.
Hi: I am 61 yrs old. ( Although my hair has been thinning gradually I am all of a sudden shocked about how much of it is gone. I don’t loose a lot–between 10-15 a day probably but I see small areas without any hair grow where I usede have hair sa. I am sure that I am not growing any hair anymore. I have not seen any doctors about it yet but from reading about it I know my hair loss/thinning is due to many medications I have been using that I need to use; antidepressant/tyroid/cholesterol but most mportantly glaucoma medication which my doctor has increased the dosage due to the aggresive nature of it. Of course I am gong to talk to him as well as my family physician. But readign what ting has been very helpful. I will post my findings when I know more. Thanks everyone

Hello Ladies. I love this site. I will be brief. I have only been to 1 Endo and they told me my glucose was pre diabetic but that my TESTOSTERONE was too high. Not over the line but right there. He put me on the cure all of metformin but I haven’t taken it yet. I am trying to lower my testosterone by diet and exercise and also watching everything I eat. Its not doing much but I have been doing this for about a month now. The holidays kill me with wine, coffee, and sweets. I have read the reviews and will probably pick up that book but also hit another endo and a dermo. You guys keep the faith. PS In Houston. Any suggestions on a dermo or endo you like, shoot them my way.


Hair: It’s a natural part of being a human. But when the temperature climbs, and skin is exposed, it’s one of those things that a good many of us want to control. This week, we’re tackling hairlessness, not just the process of hair removal (electric shavers and ingrown-hair treatments and aesthetician-approved tweezers) but also what to buy when you’re losing your hair, and even how to take care of a Sphynx cat. Here, we’re talking to dermatologists and hair-loss doctors about hair-loss treatments that actually work.
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