In 2010, a genome-wide association study was completed that identified 129 single nucleotide polymorphisms that were associated with alopecia areata. The genes that were identified include those involved in controlling the activation and proliferation of regulatory T cells, cytotoxic T lymphocyte-associated antigen 4, interleukin-2, interleukin-2 receptor A, and Eos (also known as Ikaros family zinc finger 4), as well as the human leukocyte antigen. The study also identified two genes, PRDX5 and STX17, that are expressed in the hair follicle.[18]
I was searching the internet and came across this wonderful site. I really appreciate you posting this article. I have always had a small bald patch on one side of my head. My mom told me it had always been there so I didn’t worry about it. Recently it has been getting larger and the hair around it is getting lighter. On the other side my hair is thinning and the color and texture is changing. It also seems to be falling out. I have excessive hair loss on a regular basis. I am only 24 years old and I can’t stand that my hair is falling out. I went to the dermatologist and he gave my injections but they didn’t work. He said I have alopecia areata and that the other side was a normal receding hairline. (He barely even looked at it) He then told me after the injections weren’t working to try Rogaine. I think it might be helpful to see an endrocrinologist as I have also been having problems with anemia. Again, thank you so much for the information you have provided.
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A biopsy is rarely needed to make the diagnosis or aid in the management of alopecia areata. Histologic findings include peribulbar lymphocytic infiltrate ("swarm of bees"). Occasionally, in inactive alopecia areata, no inflammatory infiltrates are found. Other helpful findings include pigment incontinence in the hair bulb and follicular stelae, and a shift in the anagen-to-telogen ratio towards telogen.[citation needed]
I want to first write that I am not a fan of hair transplants for women, I personally think that most women with androgenetic alopecia are NOT candidates for this procedure. Having said that, I get emailed all the time from women looking for a good hair transplant surgeon. If you are deadset on having a consultation, please visit the International Alliance of Hair Restoration Surgeons. The IAHRS (http://www.iahrs.org) is an organization that selectively screens skilled and ethical hair transplant surgeons. Read my thoughts about hair transplants here.

What a helpful website, thank you ladies for sharing. I am 55 and am loosing hair by handfuls when I shampoo. I have been using Minoxodil extra strength for about 5 years and it was helping but not anymore. I also have been taking Nioxin hair vitamins and they helped for the first 3 years but not now. I am going to check out Dr Redmond like several of you recommended and head to Sallys for hair extensions also. Does anyone know of a good Dermotologist or Endo Dr. in Humble or Kingwood Tx area? Karen
Taking hair supplements can be helpful for anyone who is experiencing hair loss or hair thinning. Dendy Engelman, MD, a board-certified dermatologic surgeon at Medical Dermatology & Cosmetic Surgery in New York City, previously recommended Nutrafol, a research-backed hair supplement, to Prevention. "This uses highly concentrated botanicals to address every stage of the growth cycle," she says. Nutrafol's hair supplements include vitamin E and ashwagandha (an adaptogen that helps balance cortisol levels in the body), among others.
I’m 42 and I noticed my front top and sides thinning about a year ago – a lot coming out when brushing after washing. I went to the doctor who happened to be African-American (I’m caucasion) and she actually asked me if I wore “corn rows” a lot! Needless to say, she was worthless and just prescribed me something for dandruff, which I do not have! I went to an endocrinologist to see if my thyroid or menopause was the problem – tests turned out honky dorie! Now I can see through the top of my head when the sun shines on it (scar-y) and I’m having to cover over the temple areas with sweeps of hair from the other side (interesting, the right side is much thinner). I will say that I’ve gone through hell and back with a mentally ill young adult but if it was stress, wouldn’t it have come out quicker than just in the last year (I’ve been dealing with his illness for 7 years now)?? I’ve heard that sometimes it takes 2 or 3 blood tests and doctors to finally see that one has thyroid problems. Is this the experience of others, and would I be throwing my money away by seeing my general practitioner?
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According to the International Society of Hair Restoration Surgery, since 2004, the number of female surgical hair restoration patients worldwide increased 24 percent. Modern surgical hair restoration procedures such as Follicular Unit Transplantation (FUT) and Follicular Unit Extraction (FUE) allow surgeons to take hair from the back of the head (genetically permanent hair zone) and transplant it to the areas where balding has occurred. The reason why the hair does not fall out once transplanted in its new location is because those hair follicles take on the same characteristics as the hair in the area where it originated, the genetically permanent zone. Both approaches result in lasting outcomes. In order to know if you are a candidate, Dr. Yaker will go over your medical history and examine your hair and scalp. He will determine if you have ample, good quality hair in the permanent hair zone in order to be able to relocate those hair follicles to the areas of hair loss.
Eyebrows unfortunately is a different ball game, that is skin transplantation from skin at the back of your head where your hair grows. This means that you would have to trim your eyebrows for the rest of your life. The cost for this surgical treatment is $5000, and again covered by Care Credit. Not sure if I want to do this. I am very light blond. I may just consider permanent eye brow tatoe. I have seen beautiful work – cost around $500.
Hormonal changes and medical conditions. A variety of conditions can cause permanent or temporary hair loss, including hormonal changes due to pregnancy, childbirth, menopause and thyroid problems. Medical conditions include alopecia areata (al-o-PEE-she-uh ar-e-A-tuh), which causes patchy hair loss, scalp infections such as ringworm and a hair-pulling disorder called trichotillomania (trik-o-til-o-MAY-nee-uh).
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I’m dieing I needed someone to listen to me.I ended up leaving my home town to see an endroconologist in the city yep I had Hasimotos thyrioditis which wasn’t just one symptom I had them all serve fatigue,bad skin,nails,hair,my digestive system wasn’t working properly,that was a major shut down to my body coming from someone who always was fit and look after my body.got me on medication and away I go but wasn’t that easy,I was really sick ,my medication was being prescribed by my doctor but over medicating me ,I didn’t no much and kept returning to my doctor always feeling unwell to look after my small children being a single mum all on my own with no family and friends to help. Sick of feeling like this back to my endo for more test sick of the pain that was starting in my scalp and hair loss bad,I went of my medication because I felt better of it,well that was the biggest mistake ,he said my body would have gone into thyriod storm and would end up in ICU,and not to ever do that again.Well 8 years on the pain in my scalp s still bad, iv seen specialist about my hair told me I had alepecia 8 injection in my scalp,and what a painful night.I have hair shedding for the last 4 years and I cry a lot from the pain and the lose of hair .I have very long hair and when I plait it it’s the thickness of two pencils,bbbbbuuuuttt my doctor says there is nothing wrong with my hair,I feel like punching her. I have spent years reading books,and articles trying to fix myself but still nothing,I have seen naturopaths, physiotherapist ,psychologist to talk about the pain in my head and feeling sick all a time ,it’s like we’re do you go.So ladies in all the articles Iv read I still have no help with my hair and it seems lots out there like me.looks like we have to suck it up

But you must start these medical therapies before you lose all your hair. McAndrews likens it to brushing your teeth, in that both are preventative measures. “The sooner you start doing it, the better at slowing down this aging process,” he explains, adding, “Is toothpaste perfect? No, you’re still getting tooth decay with toothpaste, but you’re slowing down tooth decay.”


I am mostly afraid that my boyfriend will leave me now, because he found out last night, and he said he doesn’t mind it. He told me that his great grandma had the same thing. He loves me, or so he says, and acts like he does anyway, but I don’t want to lose him. I know I have had a hard time living with this, and since a friend of mine told him before I was ready to tell him, I’m afraid he thinks I’m keeping secrets, but I’m not keeping them. That’s my only one. I was just wondering if anyone else had this same thing happen to them and how they dealt with it. I am aware that this is not a relationship site, but the problem is the hair loss may scare him away. It is not something that can just be ignored, and I just wanted to know if anyone else out there knows how I feel.
I just came across this website and would welcome any recommendations on hair loss specialists in the suburbs of Philadelphia, PA. I have an appointment with my family doctor in a couple weeks, and I’m sure she’s going to run blood work. I’m a 55 yo female and have been experiencing large amounts of hair loss in the past few months. I am generally in good health with the exception of some “structural” issues (scoliosis, etc.). Thank you! 

"Others are taking hair follicles out of human scalp and growing them with dermal papilla cells," Cotsarelis says. "If they grow in culture, you might be able to recombine them with skin cells and form new follicles. This would let you expand the number of follicles you get for a hair transplant. This may not be that far off -- five to 10 years, maybe. There's very good evidence you will be able to do that."
Men, oh yeah, different ball game. Just think how much money is spent on prostate research and medication versus female cancers!!!!! This IS a male society, but just smile, that makes you feel better. Do not let this get under your skin. KNOW who you are with or without hair, you are one fabulous person, loving and shining your light on this world. Step into that, claim it, own it. Whoever is unkind to you, just love them, bless them and wish them well. They have a bigger problem than you, trust me. And the WILL bump into it one day and not know what hit them.
Hair transplants will likely lead to better results in the long run (you are introducing new hairs to the balding areas), but you’ll still need to use minoxidil or finasteride after surgery to maintain the results. Like all hair loss treatments, hair transplants are best when combined with other methods, and you’ll want to speak with your doctor to see what combination is best for you.
Consider consultation with a dermatologist who has an interest in hair loss disorders. They can, admittedly, be difficult to find. Looks like you are about 3 hours away from a noted hair loss expert, Dr. Elise Olsen at Duke University. If it is very important to you, it may be worthwhile for you to travel. Hair loss cannot be appropriately diagnosed without a face-to-face consultation. 

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Loss of hair from the eyelashes could be caused by an underlying medical condition—or from pulling at your lashes (e.g. from curling lashes, from glues used for false lashes, and from tugging to remove mascara or false lashes). Whatever the reason, we regularly treat thinning lashes by prescribing Latisse®—the first, and only, FDA-approved treatment for thinning lashes. Our patients have reported excellent results (fuller, longer, darker lashes) with this cream. (Note: if you wear contact lenses, you can use Latisse®; you just need to remove the contact lenses before application and re-insert them at least 15 minutes after applying.) Just contact our office to speak with one of DR.DENNIS GROSS about whether Latisse® is right for you. Also important to note: Latisse® is currently in clinical trials as a treatment for hair loss on the scalp. It could be available for this use within the next couple of years.
While you won’t find a miracle shampoo on the market, nioxin and some other products can help keep your scalp in tip-top shape to improve the look of any hairs you do have left on your head. In fact, feeding your hair with the proper nutrients both inside and out can make it appear healthier, so you might consider using products with natural herbs, such as rosemary and mint.
Mistakenly thought of as a male disease, around 40% percent of women will suffer from some form of hair loss by the age of 50. A woman’s hair is an important part of her aesthetic make-up. It represents her style and taste, and frames her face while accentuating her best features. Unfortunately, most physicians don’t have answers or solutions for women who begin to lose their hair.  Plano, TX hair restoration surgeon, Dr. Joseph Yaker, understands that this can be extremely catastrophic to a woman’s self-confidence, body image and quality of life. Clinical studies have shown that psychiatric disorders such as depression and anxiety are more common in people with hair loss, especially women.
When men have hereditary hair loss, they often get a receding hairline. Many men see bald patches, especially on the top of the head. Women, on the other hand, tend to keep their hairline. They see noticeably thinning hair. The first sign of hair loss for many women is a widening part. In rare cases, men see noticeably thinning hair. And in rare cases, women can see a receding hairline or bald patches. The reasons for this are unknown.
I’m dieing I needed someone to listen to me.I ended up leaving my home town to see an endroconologist in the city yep I had Hasimotos thyrioditis which wasn’t just one symptom I had them all serve fatigue,bad skin,nails,hair,my digestive system wasn’t working properly,that was a major shut down to my body coming from someone who always was fit and look after my body.got me on medication and away I go but wasn’t that easy,I was really sick ,my medication was being prescribed by my doctor but over medicating me ,I didn’t no much and kept returning to my doctor always feeling unwell to look after my small children being a single mum all on my own with no family and friends to help. Sick of feeling like this back to my endo for more test sick of the pain that was starting in my scalp and hair loss bad,I went of my medication because I felt better of it,well that was the biggest mistake ,he said my body would have gone into thyriod storm and would end up in ICU,and not to ever do that again.Well 8 years on the pain in my scalp s still bad, iv seen specialist about my hair told me I had alepecia 8 injection in my scalp,and what a painful night.I have hair shedding for the last 4 years and I cry a lot from the pain and the lose of hair .I have very long hair and when I plait it it’s the thickness of two pencils,bbbbbuuuuttt my doctor says there is nothing wrong with my hair,I feel like punching her. I have spent years reading books,and articles trying to fix myself but still nothing,I have seen naturopaths, physiotherapist ,psychologist to talk about the pain in my head and feeling sick all a time ,it’s like we’re do you go.So ladies in all the articles Iv read I still have no help with my hair and it seems lots out there like me.looks like we have to suck it up

One of the most significant concerns for patients following a diagnosis of cancer is the side effect of losing their hair. For many, especially for those who have experienced a full, thick head of hair throughout their lifetime, the thought of losing it can be devastating. Chemotherapy treatment owes its effectiveness to a variety of powerful medications which are designed to quickly attack the compromised, cancerous cells. Unfortunately, in addition to treating cancer, the medications also attack the roots of your hair. This can cause the hair to fall out very quickly, even in large clumps, or gradually over time. Some of the most common medications leading to hair loss include:
The tricheologist advised me to take four (4) fish oil -1000 (blackmores brand) – this also helped sooth the scalp can reduced the itchiness down further. Using the B Complex and the fish oil daily I also saw more hair growth over the period of eight months and am continuing on this regime. I try aim at 300 minutes of walking a week and drinking water. I don’t drink soft drinks nor have sweets and try to avoid processed food.

Starting in my very early 20s i noticed the beginnings of my hair loss and started asking doctors about it with no hope/no answers until my 27.5 year. A local dermatologist “heard” something about the spironolactone/yaz combo and was willing to try it out -along with biotin, rogaine and omegas. I believe she helped the quality of my skin and hair, but did not help the fact that my hair continued to disappear.
Why? Unwanted hair growth (sideburns, for example) is a reported side effect of minoxidil. The belief is that a higher concentration of minoxidil would result in more unwanted hair, which is why women are instructed to use it less often. However, the study in Skin Therapy Letter reports that unwanted hair was more common in 2 percent minoxidil solutions than 5 percent, and women are instructed to use Rogaine’s 2 percent solution twice daily — so what gives?

The follicles on the sides of the scalp are more genetically resistant to DHT, which is why male pattern baldness often results in a “crown” of hair. But its downsides are serious. “With women, finasteride is not an option,” says Dr. Wolfeld. “It’s not FDA-approved for women to take, so we don’t prescribe it.” In fact, due to the drug’s effect on hormone levels, pregnant women are advised to not even touch broken or crushed tablets. 

Minoxidil (Rogaine, generic versions). This drug was initially introduced as a treatment for high blood pressure, but people who took it noticed that they were growing hair in places where they had lost it. Research studies confirmed that minoxidil applied directly to the scalp could stimulate hair growth. As a result of the studies, the FDA originally approved over-the-counter 2% minoxidil to treat hair loss in women. Since then a 5% solution has also become available when a stronger solution is need for a woman's hair loss.
Before men or women invest in hair restoration, consultation and workup by a board-certified dermatologist experienced should be performed first to rule out other medical conditions that may trigger hair thinning and second to maximize medical therapy. Full medical therapy as prescribed and outlined by a board-certified dermatologist must continue in order to protect one's investment in hair transplant such as NeoGraft hair restoration.
Thank you Diana. If you find out any more information, I would appreciate it. I have a dermatologist across the street from the Skin and Cancer Institute. I’m still not sure who to start with, the dermatologist or an endocronologist. I left a message for my PCP today to see if she is comfortable working with female hair loss or if not if she could refer me to someone who specializes in it. I will let you know what I hear back. In the meantime, thanks for your support. Take care.
Laser light therapy is not a baldness solution, and the HairMax takes a time commitment: You have to use the product for 15 minutes a day, three days a week and you have to keep using it indefinitely to get results. Still, laser light therapy has no major side effects, and may be best for men who have noticed some increased shedding and want to maintain more of the hair they have on their head.
Thank you all for sharing, For the pass years I have been having hair loss on and off. I have tried several natural treatment, example : hot oil , moist heat, acupuncture. Have seen several doctors and specialists which cost me thousands of dollars. I have insurance, but they will not accept, because they will not get pay, it is experimental my insurance paid for my lab tests. at this time my diagnosis is hypothyroidism. I am using organic foods, juicing; sunflowers seeds , pumpkin seed to make smoothie and oils from doTerra to massage my scalp. trying vitamins etc. etc. I cannot pinpoint what makes the improvement because I have used
If you do decide to start treatment to save your hair, a good place to start is with minoxidil, more commonly known as Rogaine. Don’t expect this hair-loss treatment to create luscious locks; minoxidil is better at slowing down or preventing more loss rather than promoting hair growth. But, according to Dr. Amy McMichael, professor and chair of Wake Forest Baptist Medical Center’s Department of Dermatology, it is effective “if used as recommended, with evidence of improvement seen around six to nine months.” Simply massage the foam or solution into your scalp once or twice daily, and for best results, use a formula with 5 percent concentration.
While you won’t find a miracle shampoo on the market, nioxin and some other products can help keep your scalp in tip-top shape to improve the look of any hairs you do have left on your head. In fact, feeding your hair with the proper nutrients both inside and out can make it appear healthier, so you might consider using products with natural herbs, such as rosemary and mint.
Many other agents have been used to treat alopecia areata, including minoxidil, psoralen plus ultraviolet A (PUVA), and anthralin (Anthra-Derm), but success rates vary. Anthralin, an anti-psoriatic, in combination with topical corticosteroids and/or minoxidil, is a good choice for use in children and those with extensive disease because it is relatively easy to use and clinical irritation may not be required for efficacy.6 Hairpieces and transplants may be the only options available for persons with severe disease that remains unresponsive to available medical treatments. Patients with recalcitrant, recurrent, or severe disease should be referred to a subspecialist. 

Hi I need help I am not sure what doctor I need to see, one day I started to have lots of back pain and my lower left side real bad I went to bed and when i shower lots of my hari started to fall off, I mean I loose my hair but not as much and I just wanted to cry when I saw lots and lots coming out. My hair is so thin now and you can see the bald spots im ony 35 and Im not sure if its my hormones or not. Can someone help me and let me know which doctor is best to see for hair loss
I”m sitting here reading all your letters hoping that you’ve helped someone and hoping that you can help me, too. I’m 48 and all my life I’ve been told how beautiful my hair was. I now live in S Florida and within the last couple of years I stopped styling my hair because of the heat and the humidity. I usually wear it in a ponytail (never tight – I’m sure that’s not the problem). About a year ago I noticed athat a lot of hair was on the back of my car seat.I mean A LOT.When I went home to NY I tried to style my hair like I used to and it didn’t work. It just layed there.The more I looked I noticed how thin it was. I came back to Fl and went to a dermatologist who barely looked at me and told me to try rogaine.
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